Phenol

Phenol

SCHEMBL28279448

Oc1ccccc1.c1ccc(N2CCCCC2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
MAPT P10636 5/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
HSD17B10 Q99714 4/20 0.53
ALOX15 P16050 4/20 0.53
NPC1 O15118 3/20 0.53
TP53 P04637 3/20 0.53
RAB9A P51151 3/20 0.53
LMNA P02545 3/20 0.53
HPGD P15428 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TSHR P16473 1/20 0.53
STAT1 P42224 1/20 0.53
MBTD1 Q05BQ5 1/20 0.50
L3MBTL3 Q96JM7 1/20 0.50
GAA P10253 5/20 0.49
NFKB1 P19838 2/20 0.49
PKM P14618 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28272307 0.94 MAPT (0.56) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
Cyclohexane SCHEMBL27743405 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
SCHEMBL2312380 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
Benzene SCHEMBL28818227 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
SCHEMBL1968506 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
SCHEMBL93630 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
SCHEMBL8542780 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
SCHEMBL28105340 0.89 L3MBTL1 (0.59) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
Water SCHEMBL10922019 0.86 L3MBTL1 (0.57) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15
Hydrochloric Acid SCHEMBL5417163 0.86 ALDH1A1 (0.60) ALDH1A1MAPTL3MBTL1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810047-A (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani 上海博邦医药科技有限公司 2019-05-28 CN disclosed
CN-107141840-B Near-infrared high-quantum-yield dye and preparation and application thereof 中国科学院理化技术研究所 2019-03-12 CN disclosed