Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259961 | 0.89 | MEN1 (0.47) | MEN1KMT2ATDP1CHRNB2CHRNB4 | |
| SCHEMBL28426457 | 0.88 | CHRNB2 (0.43) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27972549 | 0.87 | SMO (0.53) | MEN1KMT2ATDP1SMOL3MBTL1 | |
| SCHEMBL27972568 | 0.87 | MEN1 (0.53) | MEN1KMT2ATDP1POLBALDH1A1 | |
| SCHEMBL28391966 | 0.85 | SMN1; SMN2 (0.39) | MEN1KMT2ATDP1CHRNB2CHRNB4 | |
| SCHEMBL28419971 | 0.84 | MAPT (0.44) | MEN1KMT2ATDP1POLBALDH1A1 | |
| SCHEMBL27972608 | 0.84 | KCNK3 (0.50) | KMT2APOLBGAAALDH1A1TP53 | |
| SCHEMBL28259950 | 0.84 | NPC1 (0.51) | MEN1KMT2ATDP1CHRNB2CHRNB4 | |
| SCHEMBL28259959 | 0.84 | CHRNB2 (0.40) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27972547 | 0.84 | TSHR (0.40) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | claimed |
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-111333588-A | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-109414503-A | The pharmaceuticals for the treatment of for multiple sclerosis | 日本化学药品株式会社 | 2019-03-01 | — | — | CN | disclosed |