SCHEMBL28280301

SCHEMBL28280301

COc1ccc(OC)c(C(C)C)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 3/20 0.46
USP2 O75604 2/20 0.46
DUSP3 P51452 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
FABP3 P05413 1/20 0.42
FABP4 P15090 1/20 0.42
FABP5 Q01469 1/20 0.42
CDK1 P06493 1/20 0.41
CDK4 P11802 1/20 0.41
CCNB1 P14635 1/20 0.41
CCND1 P24385 1/20 0.41
CCNE1 P24864 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30791399 0.86 ALDH1A1 (0.49) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL28150202 0.77 PDE4B (0.49) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL4061687 0.77 NPC1 (0.42) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL30791332 0.76 KCNK3 (0.47) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL5068620 0.76 KDM4E (0.46) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL26259629 0.75 MAPT (0.52) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL355567 0.74 CA1 (0.57) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL29094452 0.74 PDE4B (0.55) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL17924579 0.74 MAPT (0.34) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL30731374 0.74 LMNA (0.43) MAPTKDM4EALDH1A1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622525-B The method for being used to prepare antiviral compound 艾伯维巴哈马有限公司 2019-02-15 CN disclosed