SCHEMBL28280342

SCHEMBL28280342

CC[Si](C)(CCCCO)O[Si](C)(CC)CCCCO

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28168200 0.93 ALDH1A1 (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL10946291 0.82 LMNA (0.56) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1043585 0.78 SMN1; SMN2 (0.33) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL733100 0.72 SMN1; SMN2 (0.36) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL4816226 0.71 LMNA (0.42) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL13318373 0.70 LMNA (0.39) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1238146 0.70 ALDH1A1 (0.30) ALDH1A1
SCHEMBL5575152 0.70 LMNA (0.39) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL7177498 0.70 LMNA (0.39) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL30956293 0.70 LMNA (0.36) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905356-B A method of preparing hydroxyl alkyl disiloxane 山东大学 2019-03-01 CN disclosed