Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318373 | 1.00 | LMNA (0.39) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7177498 | 1.00 | LMNA (0.39) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL733100 | 0.97 | SMN1; SMN2 (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL17083276 | 0.91 | LMNA (0.56) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16917016 | 0.90 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13609018 | 0.90 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7215321 | 0.90 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10440035 | 0.90 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1054599 | 0.89 | ALDH1A1 (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL30956294 | 0.88 | LMNA (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11684553-B2 | Curable composition for dental retraction | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-06-27 | — | — | US | disclosed |
| US-20180125764-A1 | KIT OF PARTS FOR CONDUCTING A DENTAL IMPRESSION AND RETRACTION PROCESS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2018-05-10 | — | — | US | disclosed |
| EP-1838758-B1 | POLYSILOXANES, METHOD OF SYNTHESIS AND OPHTHALMIC COMPOSITIONS | AMO GRONINGEN BV (NL) | 2017-04-12 | — | — | EP | disclosed |
| US-20160121101-A1 | Medical leads | MEDTRONIC, INC. | 2016-05-05 | — | — | US | disclosed |
| US-9220888-B2 | Medical leads | MEDTRONIC, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150057423-A1 | Polycarbonate-Polysiloxane Copolymer, and Method for Preparing Same | CHEIL INDUSTRIES INC. (KR) | 2015-02-26 | — | — | US | disclosed |
| US-20130261715-A1 | MEDICAL LEADS | MEDTRONIC, INC. | 2013-10-03 | — | — | US | disclosed |
| EP-1137955-B1 | PHOTOCURABLE SILOXANE POLYMERS | AMO GRONINGEN BV (NL) | 2013-01-02 | — | — | EP | disclosed |
| US-7732508-B2 | For making crowns, bridges, dentures and other oral prostheses; mixture of at least diunsaturated polysiloxane; an organohydrogensiloxane; alkylsiloxane having at least one carbinol, carboxy or amino group; condensation curing agent; and precious metal catalyst | 3M ESPE AG (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20090275722-A1 | AUTOMIXABLE PUTTY IMPRESSION MATERIAL | 3M INNOVATIVE PROPERTIES COMPANY | 2009-11-05 | — | — | US | disclosed |
| EP-1000070-B1 | SILICON-CONTAINING CHAIN EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2003-09-10 | — | — | EP | disclosed |
| US-20030088044-A1 | Photocurable siloxane polymers | ADVANCED MEDICAL OPTICS, INC. | 2003-05-08 | — | — | US | disclosed |
| US-6420452-B1 | POLYURETHANES WITH EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-07-16 | — | — | US | disclosed |
| US-6399734-B1 | INJECTABLE LENS MATERIAL; MIXTURE OF SILOXANE COPOLYMER, PHOTOINITIATOR | PHARMACIA AB (SE) | 2002-06-04 | — | — | US | disclosed |
| EP-1137955-A1 | PHOTOCURABLE SILOXANE POLYMERS | Pharmacia Groningen B.V. (NL) | 2001-10-04 | — | — | EP | disclosed |
| EP-1000070-A4 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-06-07 | — | — | EP | disclosed |
| WO-2000027790-A1 | MUTILIN COMPOUNDS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |
| EP-1000070-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000022460-A1 | PHOTOCURABLE SILOXANE POLYMERS | PHARMACIA GRONINGEN BV (NL) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999003863-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11684553-B2 | Curable composition for dental retraction | KDM2B, KDM2A, CDYL | LMNA 166/4885ALDH1A1 1790/4885HSD17B10 2345/4885 |
| US-20180125764-A1 | KIT OF PARTS FOR CONDUCTING A DENTAL IMPRESSION AND RETRACTION PROCESS | PHAX, SETDB1, CAD | LMNA 307/4885ALDH1A1 2674/4885HSD17B10 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.