Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239902 | 0.80 | MEN1 (0.52) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL1160546 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL28280395 | 0.80 | HSD17B1 (0.44) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL2240763 | 0.79 | CYP2A6 (0.47) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL71397 | 0.79 | CYP2A6 (0.65) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL20772791 | 0.78 | RAB9A (0.47) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL12581415 | 0.78 | HSD17B1 (0.63) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL8572801 | 0.78 | MEN1 (0.70) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL20746305 | 0.76 | CYP2A6 (0.47) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL177484 | 0.76 | CYP2A6 (0.47) | ALDH1A1HPGDMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336874-B | Preparation method of canagliflozin | 江苏工程职业技术学院 | 2022-03-11 | — | — | CN | claimed |
| CN-109336874-A | A kind of preparation method of canagliflozin | 江苏工程职业技术学院 | 2019-02-15 | — | — | CN | claimed |
| CN-109336874-B | Preparation method of canagliflozin | 江苏工程职业技术学院 | 2022-03-11 | — | — | CN | disclosed |
| CN-109336874-A | A kind of preparation method of canagliflozin | 江苏工程职业技术学院 | 2019-02-15 | — | — | CN | disclosed |