Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280467 | 0.94 | LMNA (0.43) | LMNAP2RX4RORCCYP2C8CYP2D6 | |
| SCHEMBL19551485 | 0.93 | LMNA (0.40) | LMNAP2RX4RORCCYP2C8CYP2D6 | |
| SCHEMBL19552716 | 0.92 | CA12 (0.49) | LMNAP2RX4RORCCA1CA2 | |
| SCHEMBL19551428 | 0.92 | P2RX4 (0.47) | LMNAP2RX4RORCNTRK1MEN1 | |
| SCHEMBL19551527 | 0.92 | P2RX4 (0.49) | LMNAP2RX4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19551440 | 0.89 | CA12 (0.52) | LMNACA1CA2CA12CA9 | |
| SCHEMBL19551721 | 0.89 | CACNA1H (0.38) | LMNAP2RX4RORCCYP2C8CYP2D6 | |
| SCHEMBL28279131 | 0.88 | NLRP3 (0.46) | P2RX4RORCCA1CA2CA12 | |
| SCHEMBL19551434 | 0.88 | ENPP1 (0.41) | P2RX4RORCCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19552037 | 0.88 | CA1 (0.40) | LMNAP2RX4RORCCYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |