Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280449 | 0.94 | LMNA (0.43) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL29716784 | 0.90 | P2RX4 (0.49) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL19552011 | 0.90 | P2RX4 (0.49) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL19551788 | 0.90 | CES2 (0.43) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL19551742 | 0.90 | P2RX4 (0.51) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL22353011 | 0.88 | LMNA (0.40) | LMNAROCK2P2RX4CYP2C8CYP2D6 | |
| SCHEMBL28279232 | 0.87 | P2RX4 (0.47) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL28280445 | 0.87 | P2RX4 (0.43) | ROCK2P2RX4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL28280448 | 0.86 | P2RX4 (0.46) | P2RX4CA1CA2CA12CA9 | |
| SCHEMBL19551485 | 0.86 | LMNA (0.40) | LMNAP2RX4CYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |