SCHEMBL282805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156696	0.87	LTA4H (0.41)	ZAP70SYKXDHMEN1KMT2A
	SCHEMBL10127075	0.86	XDH (0.42)	ZAP70SYKXDHMEN1KMT2A
	SCHEMBL10127182	0.85	XDH (0.42)	ZAP70SYKXDHPIK3CAGFER
	SCHEMBL10156080	0.82	XDH (0.40)	SYKXDH
	SCHEMBL10127150	0.81	XDH (0.46)	XDHMEN1KMT2AKDM4E
	SCHEMBL10127107	0.81	PDE4B (0.43)	EGFRSYKXDHMEN1KMT2A
	SCHEMBL10127260	0.79	PNP (0.41)	NTRK1XDHGFER
	SCHEMBL283672	0.78	EGFR (0.45)	NTRK1ZAP70EGFRNNMTPIK3CA
	SCHEMBL283027	0.78	TNF (0.44)	SYKXDHMEN1KMT2AKDM4E
	SCHEMBL13071122	0.77	NTRK1 (0.47)	NTRK1ZAP70EGFRNNMTPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.