Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17151793 | 0.80 | MAP4K3 (0.48) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| SCHEMBL15034717 | 0.80 | XDH (0.49) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| SCHEMBL4677044 | 0.79 | CHRNB2 (0.53) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| SCHEMBL27742532 | 0.79 | CHRNB2 (0.50) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| Hydrochloric Acid SCHEMBL161578 | 0.79 | XDH (0.48) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| SCHEMBL19449844 | 0.73 | MEN1 (0.46) | PLATFAAHPTGS2JAK3PTK2 | |
| Hydrochloric Acid SCHEMBL19434969 | 0.72 | MEN1 (0.45) | PLATFAAHPTGS2JAK3PTK2 | |
| Hydrochloric Acid SCHEMBL29504599 | 0.72 | MEN1 (0.45) | PLATFAAHPTGS2JAK3PTK2 | |
| SCHEMBL5763608 | 0.71 | LOXL2 (0.40) | PLATFAAHLOXL2PTGS2KDM1A | |
| SCHEMBL4170969 | 0.71 | SLC18A3 (0.52) | PLATPTGS2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415381-A | Thiazolopyridine derivatives as GPR119 agonist | 人类制药有限公司 | 2019-03-01 | — | — | CN | disclosed |