Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092762 | 0.77 | ALDH1A1 (0.36) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL29577033 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1TSHRFDPS | |
| SCHEMBL443116 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1TSHRFDPS | |
| SCHEMBL16283108 | 0.75 | DRD1 (0.43) | MAPTKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL29416937 | 0.75 | DRD1 (0.43) | MAPTKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL13568537 | 0.74 | SCN10A (0.49) | MAPTKDM4EALDH1A1RAB9ACYP1A2 | |
| SCHEMBL3467560 | 0.74 | SYK (0.34) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL7399408 | 0.73 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL7993684 | 0.73 | ALDH1A1 (0.54) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL31191421 | 0.72 | ACACB (0.36) | MAPTKDM4EALDH1A1L3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702141-A | Cyclobutyl-urea derivatives | 爱杜西亚药品有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-109476640-A | Bicyclic proline compounds | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | disclosed |