Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467323 | 0.77 | LOX (0.46) | ALDH1A1HSD17B10TSHRTDP1NAPRT | |
| SCHEMBL2566196 | 0.77 | LOXL2 (0.46) | SYKALDH1A1HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL27991102 | 0.75 | LOXL2 (0.47) | SYKALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL24998589 | 0.74 | TRPV1 (0.34) | SYKSMN1; SMN2KMONPC1RAB9A | |
| SCHEMBL28280585 | 0.74 | MAPT (0.36) | ALDH1A1TSHRKDM4ESMN1; SMN2KMO | |
| SCHEMBL23674532 | 0.73 | CA1 (0.39) | SLC40A1 | |
| SCHEMBL29774730 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRTDP1NAPRT | |
| SCHEMBL1072803 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRTDP1NAPRT | |
| SCHEMBL2304236 | 0.72 | KDM4C (0.50) | SYKALDH1A1MRGPRX4KDM4EKMO | |
| SCHEMBL20916908 | 0.71 | ABL1 (0.42) | SYKKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085968-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |