Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | UTRN | P46939 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283108 | 1.00 | DRD1 (0.43) | DRD1MAPTKDM4EALDH1A1PDE4A | |
| SCHEMBL17078106 | 0.82 | ALDH1A3 (0.47) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31191421 | 0.79 | ACACB (0.36) | MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL443116 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL29577033 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL28280585 | 0.75 | MAPT (0.36) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27958617 | 0.73 | GRM4 (0.39) | DRD1MAPTKDM4EPDE4APDE4B | |
| SCHEMBL29416918 | 0.73 | ALDH1A1 (0.54) | DRD1KDM4EALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL7399408 | 0.73 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7999562 | 0.73 | ALDH1A1 (0.54) | DRD1KDM4EALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137513-B | Pyrimidine derivatives | ASKA 制药株式会社 | 2022-03-01 | — | — | CN | disclosed |