Pyridine

Pyridine

SCHEMBL28280608

Oc1ccccc1-c1cccc2[nH]nnc12.c1ccncc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.39
MGAM O43451 3/20 0.38
GAA P10253 2/20 0.38
SI P14410 2/20 0.38
MGAM2 Q2M2H8 2/20 0.38
F7 P08709 1/20 0.38
PDE5A O76074 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ADORA2A P29274 1/20 0.34
ALOX15 P16050 1/20 0.34
METAP2 P50579 1/20 0.33
RAF1 P04049 1/20 0.33
DYRK1A Q13627 1/20 0.33
ALOX5 P09917 1/20 0.33
DCUN1D1 Q96GG9 1/20 0.32
TTR P02766 1/20 0.32
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83054 0.91 MGAM (0.43) IDO1MGAMGAASIMGAM2
SCHEMBL29501455 0.91 MGAM (0.43) IDO1MGAMGAASIMGAM2
SCHEMBL30640430 0.89 MGAM (0.42) IDO1MGAMGAASIMGAM2
SCHEMBL2726716 0.85 MGAM (0.39) IDO1MGAMGAASIMGAM2
SCHEMBL8962327 0.82 MGAM (0.39) IDO1MGAMGAASIMGAM2
SCHEMBL31437601 0.80 MGAM (0.44) IDO1MGAMGAASIMGAM2
SCHEMBL31619990 0.79 METAP2 (0.38) IDO1ALDH1A1HSD17B10METAP2DYRK1A
SCHEMBL30556736 0.79 METAP2 (0.38) IDO1ALDH1A1HSD17B10METAP2DYRK1A
SCHEMBL2037376 0.78 MAOA (0.36) IDO1MGAMGAASIMGAM2
SCHEMBL7158118 0.78 HPGD (0.41) IDO1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109337260-A A kind of transparent polyvinylidene fluoride film and its manufacturing method 常州回天新材料有限公司 2019-02-15 CN disclosed