SCHEMBL8962327

SCHEMBL8962327

Oc1ccccc1-c1cccc(O)c1-c1cccc2[nH]nnc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 3/20 0.39
GAA P10253 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
F7 P08709 1/20 0.39
IDO1 P14902 4/20 0.38
MAOA P21397 2/20 0.34
PDE5A O76074 1/20 0.34
ALOX15 P16050 3/20 0.33
HSD17B10 Q99714 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 2/20 0.33
DCUN1D1 Q96GG9 1/20 0.33
TTR P02766 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
MAOB P27338 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037376 0.94 MAOA (0.36) MGAMGAASIMGAM2F7
SCHEMBL83054 0.90 MGAM (0.43) MGAMGAASIMGAM2F7
SCHEMBL29501455 0.90 MGAM (0.43) MGAMGAASIMGAM2F7
SCHEMBL9268433 0.90 MAOA (0.38) MGAMGAASIMGAM2F7
SCHEMBL30640430 0.89 MGAM (0.42) MGAMGAASIMGAM2F7
SCHEMBL2726716 0.84 MGAM (0.39) MGAMGAASIMGAM2F7
SCHEMBL8962329 0.82 METAP2 (0.36) MGAMGAASIMGAM2MAOA
SCHEMBL8218667 0.82 HSPA5 (0.35) MGAMGAASIMGAM2IDO1
Pyridine SCHEMBL28280608 0.82 IDO1 (0.39) MGAMGAASIMGAM2F7
SCHEMBL719444 0.80 NSD2 (0.41) GAAHSD17B10ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623602-B1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEM (US) 1996-01-17 EP claimed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP claimed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US claimed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US claimed
EP-0623602-B1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEM (US) 1996-01-17 EP disclosed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP disclosed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP disclosed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US disclosed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US disclosed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US disclosed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US disclosed