SCHEMBL28280627

SCHEMBL28280627

CCCCC(C)CC[Si](OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
ACE2 Q9BYF1 1/20 0.34
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
DNM1 Q05193 2/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11213766 0.83 LMNA (0.52) LMNAACE2DNM1OPRM1
SCHEMBL13956922 0.83 LMNA (0.41) LMNAACE2
SCHEMBL4427113 0.81 LMNA (0.38) LMNA
SCHEMBL28108769 0.81 OPRM1 (0.33) LMNAACE2DNM1OPRM1
SCHEMBL19532754 0.80 LMNA (0.34) LMNAACE2CA1CA2DNM1
SCHEMBL20658051 0.79 LMNA (0.32) LMNA
SCHEMBL18888769 0.77 LMNA (0.39) LMNA
SCHEMBL31296465 0.77 LMNA (0.40) LMNAACE2
SCHEMBL18983159 0.77 MMP13 (0.41) LMNACA1CA2DNM1
SCHEMBL12804736 0.77 LMNA (0.40) LMNACA1CA2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476804-A flame retardant adhesives and sealants with improved mechanical properties SIKA技术股份公司 2019-03-15 CN disclosed