Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281977 | 0.86 | KDM4E (0.50) | ACHEBCHEHSD17B10KMT2AMEN1 | |
| SCHEMBL8574356 | 0.79 | HSD17B10 (0.55) | ACHEHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL7649523 | 0.79 | HSD17B10 (0.72) | HSD17B10KMT2AMEN1TP53KDM4E | |
| SCHEMBL6924495 | 0.78 | ACHE (0.49) | ACHEBCHEHSD17B10TP53KDM4E | |
| SCHEMBL356302 | 0.78 | PRKAA2 (0.61) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL618360 | 0.76 | ALDH1A1 (0.53) | HSD17B10KMT2AMEN1TP53KDM4E | |
| SCHEMBL28281976 | 0.73 | ACHE (0.47) | ACHEBCHEHSD17B10KMT2AMEN1 | |
| SCHEMBL2443270 | 0.73 | MEN1 (0.71) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL38662586 | 0.73 | MEN1 (0.71) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL14916910 | 0.72 | FABP4 (0.60) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422681-A | A kind of preparation method of Pitavastatin Calcium intermediate | 浙江京新药业股份有限公司 | 2019-03-05 | — | — | CN | disclosed |