Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP7 | P55210 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489109 | 0.89 | G6PD (0.61) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3917272 | 0.87 | G6PD (0.59) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| SCHEMBL27482406 | 0.87 | G6PD (0.59) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| Salicylic Acid SCHEMBL5693247 | 0.81 | ALDH1A1 (0.78) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| SCHEMBL120305 | 0.81 | G6PD (0.67) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| Salicylic Acid SCHEMBL4827260 | 0.81 | ALDH1A1 (0.86) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| Salicylic Acid SCHEMBL5874635 | 0.81 | ALDH1A1 (0.86) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| Salicylic Acid SCHEMBL19209758 | 0.81 | ALDH1A1 (0.86) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| SCHEMBL3498784 | 0.81 | G6PD (0.46) | CASP7G6PDCASP6ALDH1A1KDM4E | |
| SCHEMBL27956714 | 0.80 | G6PD (0.64) | CASP7G6PDCASP6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536677-A | The manufacturing method of ultraviolet protection overlay film | KAO CORP | 2019-12-03 | — | — | CN | disclosed |
| CN-110520100-A | The manufacturing method of ultraviolet protection overlay film | KAO CORP | 2019-11-29 | — | — | CN | disclosed |
| CN-109789086-A | Method for obtaining a dianthus extract rich in diglycosides and its use in cosmetics | 海洋生物技术公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105392811-B | Powder polymer, preparation method and its purposes as thickener | 化工产品开发公司SEPPIC | 2019-03-08 | — | — | CN | disclosed |