Biotin

SCHEMBL28281161

O=C(O)C(Cc1ccc(O)cc1)NP(=O)=O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.60

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	6/20	0.60

▸	MEN1	O00255	1/20	0.60

▸	ABL1	P00519	1/20	0.60

▸	LMNA	P02545	1/20	0.60

▸	PKM	P14618	1/20	0.60

▸	IDE	P14735	1/20	0.60

▸	MAPK1	P28482	1/20	0.60

▸	KMT2A	Q03164	1/20	0.60

▸	RIN1	Q13671	1/20	0.60

▸	L3MBTL1	Q9Y468	1/20	0.60

▸	CA12	O43570	7/20	0.47

▸	CA1	P00915	7/20	0.47

▸	CA2	P00918	7/20	0.47

▸	CA9	Q16790	7/20	0.47

▸	FOLH1	Q04609	5/20	0.46

▸	HLCS	P50747	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Biotin SCHEMBL3486834	0.87	TDP1 (0.59)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1672383	0.86	TDP1 (0.58)	TDP1MEN1ABL1LMNAPKM
SCHEMBL5804927	0.85	TDP1 (0.55)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL10618578	0.84	TDP1 (0.65)	TDP1MEN1ABL1LMNAPKM
SCHEMBL7259931	0.80	TDP1 (0.49)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23124079	0.80	TDP1 (0.81)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL7749208	0.80	TDP1 (0.69)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1757916	0.80	TDP1 (0.69)	TDP1MEN1ABL1LMNAPKM
SCHEMBL5808600	0.78	TDP1 (0.57)	TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL723192	0.77	TDP1 (0.90)	TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-109415435-A	Novel antibodies form	豪夫迈·罗氏有限公司	2019-03-01	—	—	CN	disclosed