SCHEMBL5808600

SCHEMBL5808600

O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ ABL1 P00519 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ PKM P14618 1/20 0.57
▸ IDE P14735 1/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ RIN1 Q13671 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ CA12 O43570 8/20 0.54
▸ CA1 P00915 8/20 0.54
▸ CA2 P00918 8/20 0.54
▸ CA9 Q16790 8/20 0.54
▸ FOLH1 Q04609 3/20 0.53
▸ PTPRF P10586 2/20 0.51
▸ PTPN2 P17706 2/20 0.51
▸ PTPN1 P18031 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5804927 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378143 0.86 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL4624128 0.86 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL29400740 0.86 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL5806608 0.85 SLC6A4 (0.54) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378084 0.85 TDP1 (0.63) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378057 0.84 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL31248180 0.84 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378085 0.84 TDP1 (0.63) TDP1MEN1ABL1LMNAPKM
SCHEMBL6974265 0.83 CASP3 (0.56) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171770-A1 METHOD FOR SCREENING FOR SEQUENCE THAT REGULATES DISPLAY EFFICIENCY IN POLYNUCLEOTIDE PRESENTATION METHOD NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-05-29 — — US disclosed
CN-119470877-A Biotinylation modified amino acid probe, preparation method and application thereof, and method and application for identifying amino acid binding protein 同济大学 2025-02-18 — — CN disclosed
WO-2025006976-A2 MRNA DISPLAY LIBRARIES AND METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-01-02 — — WO disclosed
US-20240342207-A1 MODIFIED NUCLEIC ACID COMPOSITIONS AND ASSOCIATED METHODS FOR TREATMENT OF PHENYLKETONURIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-17 — — US disclosed
WO-2024112880-A1 B7-H3 TARGETING LIGANDS AND METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-05-30 — — WO disclosed
WO-2023162983-A1 METHOD FOR SCREENING FOR SEQUENCE THAT REGULATES DISPLAY EFFICIENCY IN POLYNUCLEOTIDE PRESENTATION METHOD 国立大学法人東海国立大学機構 2023-08-31 — — WO disclosed
WO-2023015175-A1 MODIFIED NUCLEIC ACID COMPOSITIONS AND ASSOCIATED METHODS FOR TREATMENT OF PHENYLKETONURIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-02-09 — — WO disclosed
US-10745692-B2 Production method for charged non-protein amino acid-containing peptide THE UNIVERSITY OF TOKYO (JP) 2020-08-18 — — US disclosed
US-20160289668-A1 Production Method for Charged Non-Protein Amino Acid-Containing Peptide THE UNIVERSITY OF TOKYO (JP) 2016-10-06 — — US disclosed
EP-3031915-A1 PRODUCTION METHOD FOR CHARGED NON-PROTEIN AMINO ACID-CONTAINING PEPTIDE The University of Tokyo (JP) 2016-06-15 — — EP disclosed
WO-2015019999-A1 PRODUCTION METHOD FOR CHARGED NON-PROTEIN AMINO ACID-CONTAINING PEPTIDE 国立大学法人東京大学 (JP) 2015-02-12 — — WO disclosed
WO-2006121234-A1 BIOTIN-AMINO ACID CONJUGATE USEFUL AS A HYDROGELATOR AND HYDROGEL PREPARED THEREFROM POSTECH FOUNDATION (KR) 2006-11-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342207-A1 MODIFIED NUCLEIC ACID COMPOSITIONS AND ASSOCIATED METHODS FOR TREATMENT OF PHENYLKETONURIA PAH, ALKBH1, METTL16 TDP1 199/4885MEN1 3943/4885ABL1 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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