SCHEMBL28281237

SCHEMBL28281237

CCCCc1cccc(C(=O)OC)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
LMNA P02545 2/20 0.48
HSD17B10 Q99714 3/20 0.47
CFTR P13569 1/20 0.47
TSHR P16473 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PPARA Q07869 2/20 0.43
RIPK1 Q13546 1/20 0.42
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARG P37231 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637487 0.95 PPARA (0.48) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL28280190 0.91 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL15528607 0.85 ALDH1A1 (0.55) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL28602248 0.85 BID (0.49) ALDH1A1LMNAHSD17B10TSHRPPARA
SCHEMBL1789262 0.84 ALDH1A1 (0.66) ALDH1A1LMNAHSD17B10CFTRTSHR
Diethylamine SCHEMBL27732536 0.84 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2
SCHEMBL19094486 0.83 ALDH1A1 (0.49) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL31212857 0.83 PPARA (0.50) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL20476363 0.83 ALDH1A1 (0.49) ALDH1A1LMNAHSD17B10CFTRTSHR
SCHEMBL8558757 0.83 BID (0.45) ALDH1A1LMNAHSD17B10TSHRPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN disclosed