SCHEMBL15528607

SCHEMBL15528607

CCc1cccc(C(=O)OC)c1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
HSD17B10 Q99714 3/20 0.55
CFTR P13569 1/20 0.55
LMNA P02545 3/20 0.50
HTT P42858 2/20 0.49
TSHR P16473 2/20 0.47
KMT2A Q03164 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA5A P35218 1/20 0.45
CA9 Q16790 1/20 0.45
KDM4E B2RXH2 5/20 0.44
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
GAA P10253 3/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
ALOX15 P16050 1/20 0.44
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851634 0.89 ALDH1A1 (0.55) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL29424088 0.89 ALDH1A1 (0.55) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL28280190 0.88 ALDH1A1 (0.50) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL1035344 0.88 ALDH1A1 (0.53) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL15845989 0.86 ALDH1A1 (0.51) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL28281237 0.85 ALDH1A1 (0.48) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL3676590 0.85 LMNA (0.55) ALDH1A1HSD17B10CFTRLMNATSHR
Hydrochloric Acid SCHEMBL6475587 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10CFTRLMNAHTT
SCHEMBL2895994 0.85 ALDH1A1 (0.67) ALDH1A1HSD17B10CFTRLMNATSHR
SCHEMBL28637487 0.84 PPARA (0.48) ALDH1A1HSD17B10CFTRLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-B Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins 马萨诸塞大学 2022-08-05 CN claimed
EP-3481899-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN The University of Massachusetts (US) 2019-05-15 EP claimed
WO-2018008003-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS (US) 2018-01-11 WO claimed
EP-3481899-B1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN UNIV MASSACHUSETTS (US) 2022-12-21 EP disclosed
CN-109415553-B Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins 马萨诸塞大学 2022-08-05 CN disclosed
US-11077090-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (MA) 2021-08-03 US disclosed
US-11077090-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (MA) 2021-08-03 US disclosed
US-10913844-B2 Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin THE UNIVERSITY OF MASSACHUSETTS (US) 2021-02-09 US disclosed
EP-3668962-A1 FRAGRANCE RELEASE COMPOSITION Symrise AG (DE) 2020-06-24 EP disclosed
US-20190309159-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS 2019-10-10 US disclosed
EP-3490607-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF Sunovion Pharmaceuticals Inc. (US) 2019-06-05 EP disclosed
US-9452973-B2 Modulators of the relaxin receptor 1 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-09-27 US disclosed
EP-3049409-A1 ETHYNYL DERIVATIVES F. Hoffmann-La Roche AG (CH) 2016-08-03 EP disclosed
US-20160207890-A1 ETHYNYL DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2016-07-21 US disclosed
CN-104780901-A Oral composition LION CORP 2015-07-15 CN disclosed
US-20150119426-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES 2015-04-30 US disclosed
WO-2015044075-A1 ETHYNYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2015-04-02 WO disclosed
EP-2844345-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 The United States of America, as Represented by The Secretary, Department of Health and Human Services (US) 2015-03-11 EP disclosed
CN-103826605-A Oral composition LION CORP 2014-05-28 CN disclosed
WO-2013165606-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2013-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119426-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 RXFP1, RXFP2, RXFP3 ALDH1A1 2561/4885HSD17B10 2635/4885CFTR 236/4885
US-20160207890-A1 ETHYNYL DERIVATIVES GRM2, GRIA4, GRM4 ALDH1A1 1383/4885HSD17B10 3125/4885CFTR 921/4885
US-11077090-B2 Compounds and compositions and uses thereof ACHE, CHAT, MAOB ALDH1A1 173/4885HSD17B10 465/4885CFTR 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.