SCHEMBL2828165

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2717811	0.90	MAPT (0.47)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2717383	0.89	ALDH1A1 (0.49)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2719651	0.89	ALDH1A1 (0.56)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2828651	0.89	ALDH1A1 (0.46)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2719342	0.86	ALDH1A1 (0.49)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2828653	0.85	ALDH1A1 (0.43)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL1354705	0.84	ALDH1A1 (0.56)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2825650	0.83	ALDH1A1 (0.44)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2717804	0.83	TDP1 (0.59)	ALDH1A1TP53TSHRMAPTHPGD
	SCHEMBL2719364	0.82	ALDH1A1 (0.43)	ALDH1A1TP53TSHRMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.