Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109306 | 0.78 | GRM1 (0.37) | GPR119LIPCLIPGBCHE | |
| SCHEMBL17674307 | 0.77 | NR1H2 (0.40) | GPR119LIPCLIPGROCK2BCHE | |
| SCHEMBL15687908 | 0.76 | POLB (0.38) | GPR119LIPCLIPGBCHEFAAH | |
| SCHEMBL11911366 | 0.75 | GPR119 (0.39) | GPR119BCHE | |
| SCHEMBL7528678 | 0.75 | ESR2 (0.40) | GPR119BCHE | |
| SCHEMBL14164212 | 0.75 | GPR119 (0.48) | GPR119LIPCLIPGBCHE | |
| SCHEMBL2726600 | 0.74 | SCN3A (0.37) | GPR119LIPCLIPGBCHE | |
| SCHEMBL12593934 | 0.73 | NR1H2 (0.41) | GPR119LIPCLIPGBCHE | |
| SCHEMBL20033881 | 0.73 | BCHE (0.38) | GPR119BCHE | |
| SCHEMBL1018306 | 0.73 | BCHE (0.38) | GPR119BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641896-A | DIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS | 诺维拉治疗公司 | 2019-04-16 | — | — | CN | disclosed |