SCHEMBL11911366

SCHEMBL11911366

Cc1ccn(C(=O)OC(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 4/20 0.39
BCHE P06276 1/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
BUB1 O43683 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GRM5 P41594 1/20 0.34
GRM1 Q13255 1/20 0.34
ESR2 Q92731 1/20 0.34
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN6 P29350 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL28108540 0.87 KMT2A (0.36) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL7528678 0.81 ESR2 (0.40) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL21541706 0.81 BUB1 (0.37) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL28581988 0.80 BCHE (0.38) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL20033881 0.80 BCHE (0.38) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL1018306 0.80 BCHE (0.38) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL12593934 0.80 NR1H2 (0.41) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL19638080 0.79 GPR119 (0.38) GPR119BCHEKMT2AMEN1BUB1
Hydrochloric Acid SCHEMBL28584468 0.79 BCHE (0.37) GPR119BCHEKMT2AMEN1BUB1
SCHEMBL29288132 0.79 ALDH1A1 (0.42) GPR119BCHEKMT2AMEN1BUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
WO-2023131122-A1 FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2023-07-13 WO disclosed
US-20230109801-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. 2023-04-13 US disclosed
EP-4084795-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS Blue Oak Pharmaceuticals, Inc. (US) 2022-11-09 EP disclosed
WO-2022184152-A1 FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2022-09-09 WO disclosed
CN-114929228-A Compounds and compositions for treating CNS disorders 布鲁奥科制药有限公司 2022-08-19 CN disclosed
US-20160200639-A1 INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-07-14 US disclosed
EP-2487175-A1 PHARMACEUTICAL PRODUCT CONTAINING AROMATIC HETEROCYCLIC COMPOUND Kyowa Hakko Kirin Co., Ltd. (JP) 2012-08-15 EP disclosed
US-20120196854-A1 PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-08-02 US disclosed
US-20080146814-A1 Process for producing N-protected boryl compounds BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200639-A1 INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES CCNH, CTTN, CCRL2 GPR119 3887/4885BCHE 1207/4885KMT2A 1790/4885
US-20230109801-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS PMP22, CHAT, ACHE GPR119 1242/4885BCHE 49/4885KMT2A 1869/4885
US-20080146814-A1 Process for producing N-protected boryl compounds PBK, NME2, ZC3HAV1 GPR119 4559/4885BCHE 636/4885KMT2A 2651/4885
US-20120196854-A1 PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND CYP2C18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2B6 GPR119 604/4885BCHE 1739/4885KMT2A 2231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.