Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28314950 | 0.88 | GPR119 (0.40) | ESR2BCHEGPR119BUB1 | |
| SCHEMBL11911366 | 0.81 | GPR119 (0.39) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL12593934 | 0.80 | NR1H2 (0.41) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL1018306 | 0.80 | BCHE (0.38) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL20033881 | 0.80 | BCHE (0.38) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL28581988 | 0.80 | BCHE (0.38) | ESR2BCHEGPR119KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28584468 | 0.79 | BCHE (0.37) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL19638080 | 0.79 | GPR119 (0.38) | ESR2BCHEGPR119KMT2AMEN1 | |
| SCHEMBL29288132 | 0.79 | ALDH1A1 (0.42) | BCHEGPR119KMT2AMEN1BUB1 | |
| SCHEMBL16562896 | 0.77 | GPR119 (0.43) | ESR2BCHEGPR119KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004862-A | Compound, pharmaceutical composition and application thereof | 山东大学 | 2025-05-16 | — | — | CN | claimed |
| CN-117106741-A | Alcohol dehydrogenase mutant and application thereof | 清华大学 | 2023-11-24 | — | — | CN | claimed |
| CN-116355866-A | Synthesis method for synthesizing chiral hydroxypyrrolidone by enzyme catalysis | 上海罕道医药科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-0936912-A4 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 1999-10-13 | — | — | EP | claimed |
| EP-0936912-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998005336-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | claimed |
| CN-120004862-A | Compound, pharmaceutical composition and application thereof | 山东大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-118027041-A | BTK inhibitor ring derivative and preparation method and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113544130-B | BTK inhibitor ring derivative and preparation method and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117106741-A | Alcohol dehydrogenase mutant and application thereof | 清华大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-116874370-A | Carnosic acid derivative and preparation method and application thereof | 山东省药学科学院 | 2023-10-13 | — | — | CN | disclosed |
| CN-116355866-A | Synthesis method for synthesizing chiral hydroxypyrrolidone by enzyme catalysis | 上海罕道医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116355866-A | Synthesis method for synthesizing chiral hydroxypyrrolidone by enzyme catalysis | 上海罕道医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2020239103-A1 | BTK INHIBITOR RING DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2020-12-03 | — | — | WO | disclosed |
| CN-110483366-A | Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes | INST MATERIA MEDICA CAMS | 2019-11-22 | — | — | CN | disclosed |
| CN-109963848-A | Novel substituted N- (3-fluoropropyl) -pyrrolidine compounds, process for their preparation and their therapeutic use | 赛诺菲 | 2019-07-02 | — | — | CN | disclosed |
| CN-105821013-B | Carbonyl reductase and its application in the chiral N-protected-hydroxyl azacyclo- of preparation | 华东理工大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106795171-A | Antibacterial basic biaromatic derivatives with aminoalkoxy substitution | 埃科特莱茵药品有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106146511-A | Pyrazolopyrimidine derivative, preparation method, pharmaceutical composition and purposes | 安润医药科技（苏州）有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-105821013-A | Carbonyl reductase and application thereof in preparation of Chiral N-protecting-hydroxy nitrogen heterocycle | 华东理工大学 | 2016-08-03 | — | — | CN | disclosed |