Acetone

Acetone

SCHEMBL28282102

CC(=O)C(Cl)(Cl)Cl.CC(C)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
CA4 P22748 2/20 0.38
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
CA1 P00915 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136756 0.96
SCHEMBL11151294 0.92
Fluoride SCHEMBL28202487 0.92
Carbon Tetrachloride SCHEMBL4415386 0.82
Acetone SCHEMBL7644638 0.82
Acetone SCHEMBL11854533 0.80 LMNA (0.46) LMNATSHRALDH1A1TP53CA4
Trichloroacetic Acid SCHEMBL2472230 0.80 TSHR (0.77) LMNATSHRALDH1A1TP53CA4
SCHEMBL10398731 0.79 ALDH1A1 (0.37) TSHRALDH1A1TP53CA4TDP1
SCHEMBL948114 0.79 ALDH1A1 (0.37) TSHRALDH1A1TP53CA4
Trichloroethane SCHEMBL11686802 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109516908-A The method of purification and its application of 1,1,3- trichloroacetone 江西天新药业有限公司 2019-03-26 CN disclosed