SCHEMBL282824

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL328304	0.93	CHRM1 (0.50)	ALDH1A1MEN1KMT2AKCNH2DRD4
	SCHEMBL499403	0.91	NOS3 (0.50)	ALDH1A1MEN1KMT2AKCNH2DRD4
	SCHEMBL10127884	0.90	KCNH2 (0.48)	ALDH1A1MEN1KMT2AKCNH2DRD4
	SCHEMBL10127888	0.84	POLB (0.49)	ALDH1A1KCNH2CHRM5CHRM1CHRM3
	SCHEMBL10127988	0.84	KCNH2 (0.50)	ALDH1A1MEN1KMT2AKCNH2DRD4
	SCHEMBL17340322	0.82	CHRM1 (0.49)	ALDH1A1KCNH2TERTGAACHRM5
	SCHEMBL282621	0.82	TERT (0.44)	ALDH1A1MEN1KMT2AKCNH2DRD4
	SCHEMBL8130592	0.82	TERT (0.48)	ALDH1A1MEN1KMT2AKCNH2HTT
	SCHEMBL499722	0.81	NOS3 (0.50)	ALDH1A1KCNH2NOS3NOS1TERT
	SCHEMBL13071616	0.81	CHRM1 (0.47)	ALDH1A1KCNH2DRD4KCNJ1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.