Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.70 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.70 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156595 | 0.82 | NR4A2 (0.70) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL1093530 | 0.82 | NR4A2 (1.00) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL28068117 | 0.82 | NR4A2 (0.70) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL30031033 | 0.82 | NR4A2 (1.00) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| Hydrochloric Acid SCHEMBL28254334 | 0.81 | NR4A2 (0.97) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL23269495 | 0.79 | GPR84 (0.71) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL27966043 | 0.79 | NR4A2 (0.66) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL28465934 | 0.79 | ALDH1A1 (0.67) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL4954977 | 0.79 | GPR84 (0.77) | NR4A2CREBBPGPR84ALDH1A1PBRM1 | |
| SCHEMBL64182 | 0.79 | GPR84 (0.77) | NR4A2CREBBPGPR84ALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400617-A | A kind of new indole and pyranone framework compound and preparation method thereof | 湖北大学 | 2019-03-01 | — | — | CN | disclosed |