Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109779 | 0.84 | SLC22A1 (0.52) | SLC22A1PPARGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1649434 | 0.84 | SLC22A1 (0.52) | SLC22A1PPARGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28212600 | 0.84 | PTGS2 (0.46) | SLC22A1PTGS2PTGS1CYP19A1MAPK1 | |
| SCHEMBL4192926 | 0.84 | LMNA (0.55) | CHRM2CHRM4CHRM1CHRM3PTGS2 | |
| SCHEMBL30190308 | 0.83 | SLC22A1 (0.51) | SLC22A1PPARGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21359744 | 0.82 | SLC22A1 (0.42) | SLC22A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7623367 | 0.82 | CHRM1 (0.46) | CHRM2CHRM4CHRM1CHRM3PTGS2 | |
| SCHEMBL27515436 | 0.82 | LMNA (0.47) | SLC22A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10445350 | 0.82 | CHRM1 (0.46) | CHRM2CHRM4CHRM1CHRM3PTGS2 | |
| SCHEMBL2296619 | 0.81 | ALDH1A1 (0.56) | PTGS2PTGS1GPR88LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109486897-A | A kind of method that stereoselectivity enzymatic hydrolysis splits 2- phenylpropionic acid enantiomer | 湖南理工学院 | 2019-03-19 | — | — | CN | claimed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |