Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281987 | 0.78 | CYP19A1 (0.35) | ALDH1A1POLBCYP19A1 | |
| SCHEMBL20850849 | 0.73 | HRH3 (0.45) | ALDH1A1GAAHSP90AA1POLBCYP19A1 | |
| SCHEMBL7034434 | 0.73 | ALDH1A1 (0.41) | ALDH1A1GAAHSP90AA1POLBCYP19A1 | |
| SCHEMBL29219009 | 0.71 | SNCA (0.43) | ALDH1A1GAAPOLBSMN1; SMN2SIRT2 | |
| SCHEMBL30123443 | 0.71 | SNCA (0.49) | ALDH1A1GAAPOLBSIRT2LMNA | |
| SCHEMBL499297 | 0.69 | NOS3 (0.48) | ALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL26706259 | 0.69 | GAA (0.48) | ALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL7118284 | 0.68 | ALDH1A1 (0.41) | ALDH1A1POLBCYP19A1SMN1; SMN2AR | |
| SCHEMBL7118260 | 0.68 | ALDH1A1 (0.41) | ALDH1A1POLBCYP19A1SMN1; SMN2AR | |
| SCHEMBL7118257 | 0.68 | ALDH1A1 (0.41) | ALDH1A1POLBCYP19A1SMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |