Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283586 | 0.78 | ALDH1A1 (0.41) | CYP19A1ALDH1A1POLB | |
| SCHEMBL7035610 | 0.69 | CYP19A1 (0.35) | CYP19A1NFE2L2ACHEHTR4OPRD1 | |
| SCHEMBL19639710 | 0.69 | MAPT (0.38) | ALDH1A1MEN1KMT2AADRA2AADRA2B | |
| SCHEMBL30790657 | 0.68 | MEN1 (0.40) | ALDH1A1POLBMEN1KMT2AADRA2A | |
| SCHEMBL499065 | 0.65 | NOS3 (0.58) | ACHEALDH1A1POLBDRD3 | |
| Hydrochloric Acid SCHEMBL19896259 | 0.64 | NPC1 (0.40) | CYP19A1NFE2L2ACHEHTR4OPRD1 | |
| SCHEMBL499955 | 0.63 | NOS3 (0.57) | ACHEALDH1A1POLB | |
| SCHEMBL15712192 | 0.63 | HTR7 (0.43) | CYP19A1NFE2L2ACHEHTR4ALDH1A1 | |
| SCHEMBL499200 | 0.63 | NOS3 (0.62) | OPRM1OPRK1ADRA2AADRA2BADRA2C | |
| SCHEMBL1746035 | 0.62 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |