Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283515 | 0.86 | ALDH1A1 (0.65) | KMT2AALDH1A1MEN1GAAL3MBTL1 | |
| SCHEMBL28285201 | 0.85 | ALDH1A1 (0.68) | KMT2AALDH1A1MEN1GAAL3MBTL1 | |
| SCHEMBL856792 | 0.83 | PKM (0.66) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL29507905 | 0.83 | PKM (0.66) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL6951550 | 0.83 | GAA (0.69) | KMT2AALDH1A1MEN1GAAL3MBTL1 | |
| SCHEMBL1592638 | 0.82 | ALDH1A1 (0.63) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL28871030 | 0.82 | POLB (0.59) | KMT2AALDH1A1MEN1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2544298 | 0.81 | ALDH1A1 (0.62) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL20246801 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1MEN1GAAL3MBTL1 | |
| SCHEMBL30023094 | 0.80 | KMT2A (0.65) | KMT2AALDH1A1MEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015984-A | Substituted (E)-N '-(1- phenylethylene) benzoyl hydrazine analog as histone demethylase inhibitor | 犹他大学研究基金会 | 2019-07-16 | — | — | CN | disclosed |
| CN-105555784-B | Substituted (E) -N' - (1-phenylethylene) benzoyl hydrazine analogs as histone demethylase inhibitors | 犹他大学研究基金会 | 2019-03-15 | — | — | CN | disclosed |