Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283515 | 0.98 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL28871030 | 0.85 | POLB (0.59) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL28283602 | 0.85 | KMT2A (0.59) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL12852518 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL264656 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL396589 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL6945990 | 0.80 | USP2 (0.71) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL8982209 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL208148 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11936027 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015984-A | Substituted (E)-N '-(1- phenylethylene) benzoyl hydrazine analog as histone demethylase inhibitor | 犹他大学研究基金会 | 2019-07-16 | — | — | CN | disclosed |
| CN-105555784-B | Substituted (E) -N' - (1-phenylethylene) benzoyl hydrazine analogs as histone demethylase inhibitors | 犹他大学研究基金会 | 2019-03-15 | — | — | CN | disclosed |