Pivalate

Pivalate

SCHEMBL28284292

CC(C)(C)C(=O)O.O=C(NCC1CCNC1)OCc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.50
ITGA2B P08514 6/20 0.50
ITGAV P06756 1/20 0.46
CHRM3 P20309 2/20 0.46
BRD4 O60885 1/20 0.46
CCKBR P32239 1/20 0.45
HTR2C P28335 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
F2 P00734 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3982387 0.93 CCKBR (0.50) ITGB3ITGA2BITGAVCHRM3CCKBR
SCHEMBL12723408 0.93 CCKBR (0.50) ITGB3ITGA2BITGAVCHRM3CCKBR
Trifluoroacetic Acid SCHEMBL13739250 0.91 F2 (0.51) ITGB3ITGA2BITGAVCHRM3CCKBR
Tert-Butyl Formate SCHEMBL28284338 0.89 ITGB3 (0.47) ITGB3ITGA2BITGAVCHRM3BRD4
SCHEMBL12722664 0.86 ALDH1A1 (0.50) CCKBRHTR2CALDH1A1LMNASMN1; SMN2
SCHEMBL5338500 0.86 ALDH1A1 (0.50) CCKBRHTR2CALDH1A1LMNASMN1; SMN2
SCHEMBL12722614 0.86 ALDH1A1 (0.50) CCKBRHTR2CALDH1A1LMNASMN1; SMN2
SCHEMBL3947594 0.85 BRD4 (0.52) ITGB3ITGA2BITGAVBRD4CCKBR
Hydrochloric Acid SCHEMBL6307871 0.85 ALDH1A1 (0.49) CCKBRHTR2CALDH1A1LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL3947595 0.84 BRD4 (0.51) ITGB3ITGA2BITGAVBRD4CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790157-A New antimicrobial compound 方济各安吉利克化学联合股份有限公司 2019-05-21 CN disclosed
CN-109415373-A New antimicrobial compound 方济各安吉利克化学联合股份有限公司 2019-03-01 CN disclosed