Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043219 | 0.82 | ALDH1A1 (0.52) | L3MBTL1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28228710 | 0.79 | HSD17B3 (0.58) | L3MBTL1KMT2ASMN1; SMN2ALDH1A1HSD17B3 | |
| SCHEMBL19287121 | 0.76 | L3MBTL1 (0.70) | L3MBTL1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL29062360 | 0.75 | PTGS1 (0.45) | L3MBTL1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27968649 | 0.74 | GSK3B (0.55) | ALDH1A1THRATHRB | |
| SCHEMBL11525096 | 0.74 | NPC1 (0.64) | L3MBTL1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28234292 | 0.74 | SMN1; SMN2 (0.50) | L3MBTL1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9110541 | 0.74 | GSK3B (0.55) | L3MBTL1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2118360 | 0.74 | KMT2A (0.66) | L3MBTL1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5731669 | 0.74 | GSK3B (0.55) | KMT2ARAB9ANPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475593-A | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109475593-A | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | disclosed |