Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131545 | 0.91 | PHGDH (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27486134 | 0.88 | PHGDH (0.71) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27774576 | 0.87 | ALDH1A1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7131844 | 0.81 | PHGDH (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27756136 | 0.76 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL153130 | 0.73 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6797104 | 0.73 | POLB (0.54) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8741146 | 0.73 | LMNA (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2084284 | 0.72 | ATM (0.51) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11776464 | 0.72 | CA2 (0.38) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109568595-A | Nucleic acid-drug conjugates, drug delivery system and its preparation method and application | 上海交通大学 | 2019-04-05 | — | — | CN | claimed |
| CN-109568595-A | Nucleic acid-drug conjugates, drug delivery system and its preparation method and application | 上海交通大学 | 2019-04-05 | — | — | CN | disclosed |