SCHEMBL28285243

SCHEMBL28285243

CCOC(=O)c1c(-c2ccccc2)[nH]c2cc(N)ccc12

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
MAPT P10636 3/20 0.65
HPGD P15428 3/20 0.65
GAA P10253 2/20 0.65
KDM4E B2RXH2 1/20 0.65
MEN1 O00255 1/20 0.65
LMNA P02545 1/20 0.65
MAPK10 P53779 1/20 0.65
KMT2A Q03164 1/20 0.65
HSD17B10 Q99714 1/20 0.65
ALOX5 P09917 9/20 0.52
PTGES O14684 6/20 0.52
SMN1; SMN2 Q16637 1/20 0.48
CSF1R P07333 1/20 0.47
GRM6 O15303 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6495407 0.86 NR4A2 (0.50) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL30482846 0.85 ALDH1A1 (0.76) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL23606247 0.83 GAA (0.60) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL14710592 0.78 MAPT (0.62) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL6954432 0.78 ALDH1A1 (0.76) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL5330015 0.77 KDM5A (0.64) ALDH1A1KDM4E
SCHEMBL6300719 0.76 ALDH1A1 (0.67) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL7215720 0.74 ALOX5 (0.56) ALDH1A1MAPTHPGDGAAKDM4E
Hydrochloric Acid SCHEMBL11463651 0.74 MAPT (0.53) ALDH1A1MAPTHPGDGAAKDM4E
SCHEMBL4701132 0.73 KDM5A (0.59) ALDH1A1MAPTHPGDGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111251500-B Foaming polymer particles with skin dilatancy and preparation method thereof 厦门天策材料科技有限公司 2024-10-22 CN disclosed
CN-111253583-B Dilatant hybrid dynamic polymer and dilatant realization method thereof 厦门天策材料科技有限公司 2023-05-16 CN disclosed
CN-111378138-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378168-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378159-A Energy absorption method and material based on hybrid cross-linked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111378160-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378169-A Force-induced response hybrid crosslinked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111378163-A Combined hybrid dynamic polymer and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111040202-A Combined hybrid dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
CN-111040110-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
CN-109666161-A A kind of energy-absorbing method based on dynamic aggregation object 翁秋梅 2019-04-23 CN disclosed
CN-109666157-A A kind of hydridization dynamic aggregation object and its application 翁秋梅 2019-04-23 CN disclosed