Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652643 | 0.79 | CYP19A1 (0.55) | NFE2L2CYP19A1MAOAMAOBPKM | |
| SCHEMBL28522806 | 0.70 | SMN1; SMN2 (0.37) | NFE2L2CYP19A1MAOAMAOBPTGS1 | |
| SCHEMBL27898117 | 0.69 | ALDH1A1 (0.43) | CASP3SENP8SENP7SENP6PTGS2 | |
| SCHEMBL18867936 | 0.67 | NFE2L2 (1.00) | NFE2L2CASP3SENP8SENP7CYP19A1 | |
| SCHEMBL700761 | 0.67 | NFE2L2 (1.00) | NFE2L2CASP3SENP8SENP7CYP19A1 | |
| SCHEMBL4946969 | 0.67 | NFE2L2 (1.00) | NFE2L2CASP3SENP8SENP7CYP19A1 | |
| SCHEMBL700760 | 0.67 | NFE2L2 (1.00) | NFE2L2CASP3SENP8SENP7CYP19A1 | |
| SCHEMBL7034944 | 0.67 | ALDH1A1 (0.56) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL27512901 | 0.66 | MAOB (0.56) | NFE2L2CYP19A1MAOAMAOBKMT2A | |
| SCHEMBL8848267 | 0.65 | ALDH1A1 (0.37) | CASP3SENP8SENP7SENP6BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608455-A | A kind of synthetic method of indazole simultaneously [2,3-a] quinoline and its derivates | 常州大学 | 2019-04-12 | — | — | CN | disclosed |