SCHEMBL4946969

SCHEMBL4946969

Fc1ccc(/C=C\c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 11/20 1.00
MAOB P27338 2/20 0.56
CYP19A1 P11511 1/20 0.56
MAOA P21397 1/20 0.56
APP P05067 1/20 0.54
PTGS1 P23219 1/20 0.54
RELA Q04206 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700761 1.00 NFE2L2 (1.00) NFE2L2MAOBCYP19A1MAOAAPP
SCHEMBL700760 1.00 NFE2L2 (1.00) NFE2L2MAOBCYP19A1MAOAAPP
SCHEMBL18867936 1.00 NFE2L2 (1.00) NFE2L2MAOBCYP19A1MAOAAPP
SCHEMBL13766558 0.88 NFE2L2 (0.78) NFE2L2APPPTGS1
SCHEMBL13766470 0.88 NFE2L2 (0.78) NFE2L2APPPTGS1
SCHEMBL700052 0.88 NFE2L2 (0.78) NFE2L2APPPTGS1
SCHEMBL700051 0.88 NFE2L2 (0.78) NFE2L2APPPTGS1
SCHEMBL22468800 0.88 NFE2L2 (0.78) NFE2L2APPPTGS1
SCHEMBL11547655 0.85 NFE2L2 (0.72) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL44504 0.85 NFE2L2 (0.72) NFE2L2MAOBCYP19A1MAOARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043793-B1 Secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2008-04-02 EP claimed
US-6303250-B1 BATTERIES USING NONAQUEOUS ELECTROLYTIC SOLUTION; HIGH TEMPERATURE STORAGE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-10-16 US claimed
EP-1043793-A2 Secondary battery Matsushita Electric Industrial Co., Ltd. (JP) 2000-10-11 EP claimed
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-02 US disclosed
EP-2810198-B1 ANTI-INVASIVE COMPOUNDS UNIV GENT (BE) 2023-07-12 EP disclosed
WO-2020198464-A1 HIGHLY SELECTIVE ELECTROCHEMICAL HYDROGENATION OF ALKYNES THE TRUSTEES OF INDIANA UNIVERSITY (US) 2020-10-01 WO disclosed
US-9290427-B2 Anti-invasive compounds UNIVERSITEIT GENT (BE) 2016-03-22 US disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-20150011620-A1 ANTI-INVASIVE COMPOUNDS UNIVERSITEIT GENT (BE) 2015-01-08 US disclosed
EP-2810198-A1 ANTI-INVASIVE COMPOUNDS Universiteit Gent (BE) 2014-12-10 EP disclosed
WO-2013113722-A1 ANTI-INVASIVE COMPOUNDS UNIVERSITEIT GENT (BE) 2013-08-08 WO disclosed
EP-1043793-B1 Secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2008-04-02 EP disclosed
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents REGENTS OF THE UNIVERSITY OF NEW MEXICO 2007-10-25 US disclosed
US-6303250-B1 BATTERIES USING NONAQUEOUS ELECTROLYTIC SOLUTION; HIGH TEMPERATURE STORAGE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-10-16 US disclosed
JP-2000299125-A NONAQUEOUS ELECTROLYTE SECONDARY BATTERY MATSUSHITA ELECTRIC IND CO LTD 2000-10-24 JP disclosed
EP-1043793-A2 Secondary battery Matsushita Electric Industrial Co., Ltd. (JP) 2000-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents TGFB1, VHL, TMSB10 NFE2L2 68/4885MAOB 1359/4885CYP19A1 143/4885
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease ADM2, DDAH1, BHMT NFE2L2 713/4885MAOB 544/4885CYP19A1 445/4885
US-20150011620-A1 ANTI-INVASIVE COMPOUNDS MMP3, MMP10, MIF NFE2L2 1215/4885MAOB 4150/4885CYP19A1 2401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.