Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719764 | 0.91 | NOTUM (0.49) | NOTUMMAPK1KDM4EGAAMEN1 | |
| SCHEMBL28016911 | 0.81 | MAPK1 (0.47) | NOTUMMAPK1KDM4EGAAMEN1 | |
| SCHEMBL3491824 | 0.78 | NOTUM (0.61) | NOTUMKDM4ETDP1L3MBTL1POLB | |
| SCHEMBL4783773 | 0.77 | NOTUM (0.47) | NOTUMMAPK1KDM4EMAPTTDP1 | |
| SCHEMBL3492555 | 0.72 | NR4A2 (0.56) | NOTUMMAPK1KDM4EGAAMEN1 | |
| SCHEMBL28037281 | 0.72 | NOTUM (0.51) | NOTUMMAPK1KDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL31255509 | 0.70 | BCAT2 (0.79) | KDM4EMEN1KMT2ANPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL18049957 | 0.70 | BCAT2 (0.52) | KDM4EMAPTL3MBTL1BCAT2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL1786045 | 0.70 | BCAT2 (0.79) | KDM4EMEN1KMT2ANPC1MAPT | |
| SCHEMBL28686718 | 0.70 | MAPK1 (0.47) | MAPK1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408321-B | Indoles and azole derivatives, their preparation method and the pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-08 | — | — | CN | disclosed |