Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635688 | 0.76 | KDM4E (0.44) | FFAR1KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL28285419 | 0.75 | AR (0.53) | FFAR1KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL3640380 | 0.75 | TDP1 (0.41) | ALDH1A1LMNATSHRMAPT | |
| SCHEMBL30875863 | 0.74 | PPARG (0.66) | FFAR1KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL3017400 | 0.74 | PPARG (0.66) | FFAR1KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL11540235 | 0.73 | ALDH1A3 (0.43) | ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL28855741 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTHTT | |
| SCHEMBL9191388 | 0.70 | CYP3A4 (0.44) | KDM4EALDH1A1PPARGPPARALMNA | |
| SCHEMBL10487443 | 0.70 | KMT2A (0.55) | FFAR1ALDH1A1PPARGPPARALMNA | |
| SCHEMBL27515605 | 0.70 | TSHR (0.49) | KDM4EALDH1A1LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563071-A | Chemical compound as ATF4 approach restrainer | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |