Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22104103 | 0.93 | EPHX2 (0.68) | SMN1; SMN2PKMHTTALDH1A1EPHX2 | |
| SCHEMBL16018991 | 0.85 | PKM (0.60) | SMN1; SMN2PKMHTTALDH1A1EPHX2 | |
| SCHEMBL17658614 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL3948461 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1CA1 | |
| SCHEMBL381922 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1CA1 | |
| SCHEMBL3948456 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1CA1 | |
| Methoxyamine SCHEMBL5122725 | 0.81 | TSHR (0.75) | ALDH1A1GAATSHREPHX1CA1 | |
| SCHEMBL15495455 | 0.80 | PKM (0.60) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL28135182 | 0.80 | ALDH1A1 (0.83) | ALDH1A1GAATSHREPHX1CA1 | |
| SCHEMBL1675909 | 0.79 | EPHX2 (0.59) | SMN1; SMN2PKMHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153028-B | Compound as c-Met kinase inhibitor | 南京爱德程医药科技有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-104936946-A | Process for preparing antitumor agent 6- (7- ((1-aminocyclopropyl) methoxy) -6-methoxyquinolin-4-yloxy) -N-methyl-1-naphthamide and crystal thereof | ADVENCHEN PHARMACEUTICALS LLC | 2015-09-23 | — | — | CN | disclosed |