Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139722 | 0.88 | ACHE (0.45) | ITGB2ICAM1ITGALP2RX7LMNA | |
| SCHEMBL23189238 | 0.82 | ACHE (0.34) | ITGB2ICAM1ITGALP2RX7SLC9A1 | |
| SCHEMBL12431218 | 0.81 | P2RX7 (0.35) | ITGB2ICAM1ITGALP2RX7EED | |
| SCHEMBL30364084 | 0.79 | AHR (0.39) | P2RX7AHRADRA2ACYP2D6ADRA2B | |
| SCHEMBL30364094 | 0.79 | ITGB2 (0.44) | ITGB2ICAM1ITGALP2RX7MEN1 | |
| SCHEMBL22260971 | 0.79 | P2RX7 (0.35) | P2RX7LMNAEEDSUZ12EZH2 | |
| SCHEMBL964309 | 0.74 | ITGB2 (0.42) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL945134 | 0.74 | ITGB2 (0.42) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL2830923 | 0.74 | ITGB2 (0.42) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL5543467 | 0.74 | ITGB2 (0.42) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113122061-A | Quantum dot ink and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| EP-4713327-A1 | SPIRO DERIVATIVES AS WRN INHIBITORS | Insilico Medicine IP Limited (HK) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235292-A1 | SPIRO DERIVATIVES AS WRN INHIBITORS | INSILICO MEDICINE IP LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |
| US-20240208919-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11787775-B2 | Therapeutic compounds and methods of use | GENENTECH, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| CN-109563063-B | Method for preparing 4-substituted 2, 3-dihydro-1-benzofuran derivatives by cyclisation of 2- (2-diazonium-6-substituted phenyl) ethanoates | 拜耳作物科学股份公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-109641822-B | Process for preparing substituted styrene derivatives | 拜耳作物科学股份公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113122061-A | Quantum dot ink and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| US-11014917-B2 | 5-fluoro-c-(aryl or heterocyclyl)-glycoside derivatives useful as dual SGLT1 / SGLT2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-25 | — | — | US | disclosed |
| US-20200291004-A1 | 5-FLUORO-C-(ARYL OR HETEROCYCLYL)-GLYCOSIDE DERIVATIVES USEFUL AS DUAL SGLT1 / SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-09-17 | — | — | US | disclosed |
| US-20190055226-A1 | 5-FLUORO-C-(ARYL OR HETEROCYCLYL)-GLYCOSIDE DERIVATIVES USEFUL AS DUAL SGLT1 / SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-02-21 | — | — | US | disclosed |
| WO-2018029141-A1 | METHOD FOR PRODUCING 4-SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN DERIVATIVES BY CYLISATION OF 2-(2-DIAZONIUM-6-SUBSTITUTED PHENYL)ETHANOL SALTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-15 | — | — | WO | disclosed |
| WO-2018029141-A1 | METHOD FOR PRODUCING 4-SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN DERIVATIVES BY CYLISATION OF 2-(2-DIAZONIUM-6-SUBSTITUTED PHENYL)ETHANOL SALTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-15 | — | — | WO | disclosed |
| WO-2018029140-A1 | METHOD FOR PRODUCING SUBSTITUTED STYRENE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-15 | — | — | WO | disclosed |
| WO-2016109359-A1 | CYCLOPROPYL DIHYDROBENZOFURAN MODULATORS OF MELATONIN RECEPTORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109359-A1 | CYCLOPROPYL DIHYDROBENZOFURAN MODULATORS OF MELATONIN RECEPTORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| CN-101925589-B | Process for producing 4-vinyl-2, 3-dihydrobenzofuran | SUMITOMO CHEMICAL CO | 2013-03-27 | — | — | CN | disclosed |
| CN-101925589-A | Process for producing 4-vinyl-2, 3-dihydrobenzofuran | SUMITOMO CHEMICAL CO | 2010-12-22 | — | — | CN | disclosed |
| US-20100298584-A1 | PROCESS FOR PRODUCTION OF 4-VINYL-2,3-DIHYDROBENZOFURAN | SUMITOMO CHEMICAL COMPANY LIMITED | 2010-11-25 | — | — | US | disclosed |
| EP-2236504-A1 | PROCESS FOR PRODUCTION OF 4-VINYL-2,3-DIHYDROBENZOFURAN | Sumitomo Chemical Company, Limited (JP) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055226-A1 | 5-FLUORO-C-(ARYL OR HETEROCYCLYL)-GLYCOSIDE DERIVATIVES USEFUL AS DUAL SGLT1 / SGLT2 MODULATORS | SLC5A2, SLC5A1, SLC2A2 | ITGB2 2470/4885ICAM1 2565/4885ITGAL 2174/4885 |
| US-20200291004-A1 | 5-FLUORO-C-(ARYL OR HETEROCYCLYL)-GLYCOSIDE DERIVATIVES USEFUL AS DUAL SGLT1 / SGLT2 MODULATORS | SLC5A2, SLC5A1, SLC2A2 | ITGB2 2683/4885ICAM1 2690/4885ITGAL 2557/4885 |
| US-20240208919-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | VHL, NQO1, PCSK9 | ITGB2 3700/4885ICAM1 1822/4885ITGAL 3367/4885 |
| US-11787775-B2 | Therapeutic compounds and methods of use | VHL, NQO1, PCSK9 | ITGB2 3700/4885ICAM1 1822/4885ITGAL 3367/4885 |
| US-11014917-B2 | 5-fluoro-c-(aryl or heterocyclyl)-glycoside derivatives useful as dual SGLT1 / SGLT2 modulators | SLC5A2, SLC5A1, SLC2A2 | ITGB2 2683/4885ICAM1 2690/4885ITGAL 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.