Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.38 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2483355 | 0.98 | ITGB2 (0.41) | ITGB2ICAM1ITGALSLC9A1MEN1 | |
| SCHEMBL29509471 | 0.88 | ACHE (0.40) | ITGB2ICAM1ITGALLMNACRHBP | |
| SCHEMBL2481284 | 0.88 | ACHE (0.40) | ITGB2ICAM1ITGALLMNACRHBP | |
| Hydrochloric Acid SCHEMBL30361650 | 0.86 | ACHE (0.39) | ITGB2ICAM1ITGALLMNACRHBP | |
| Oxalic Acid SCHEMBL15844457 | 0.79 | MTNR1A (0.39) | SLC9A1MEN1KMT2ASLC9A5SLC9A2 | |
| SCHEMBL2938129 | 0.76 | MAOA (0.38) | SLC9A1MEN1KMT2ASLC9A5SLC9A2 | |
| SCHEMBL23735384 | 0.75 | CD44 (0.47) | ITGB2ICAM1ITGALSLC9A1LMNA | |
| Cadaverine Tartrate SCHEMBL14810396 | 0.74 | MTNR1A (0.36) | SLC9A1MEN1KMT2ASLC9A5SLC9A2 | |
| SCHEMBL8081108 | 0.74 | MAP3K14 (0.47) | ITGB2ICAM1ITGALSLC9A1MEN1 | |
| SCHEMBL964309 | 0.74 | ITGB2 (0.42) | ITGB2ICAM1ITGALSLC9A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483456-B | Method for synthesizing ramelteon | 武汉大学 | 2021-03-16 | — | — | CN | claimed |
| CN-110483456-A | The synthetic method of ramelteon | UNIV WUHAN | 2019-11-22 | — | — | CN | claimed |
| WO-2026103888-A1 | PYRIMIDIN-2(1H)-ONE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海青润医药科技有限公司 | 2026-05-21 | — | — | WO | disclosed |
| US-20260138985-A1 | Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders | TERRAN BIOSCIENCES INC (US) | 2026-05-21 | — | — | US | disclosed |
| CN-122036626-A | Pyrimidine-2 (1H) -ketone derivative, pharmaceutical composition and application thereof | 上海青润医药科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2026098560-A2 | BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2026-05-15 | — | — | WO | disclosed |
| US-20250326767-A1 | NOVEL BENZOTHIAZOLE DERIVATIVES | CARNA BIOSCIENCES, INC. (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | SHOUYAO HOLDINGS BEIJING CO LTD (CN) | 2025-07-10 | — | — | US | disclosed |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2025-04-10 | — | — | US | disclosed |
| US-20250115618-A1 | SULFONIMIDAMIDE COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | GENENTECH, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12234245-B2 | Sulfonimidamide compounds as inhibitors of interleukin-1 activity | GENENTECH, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| EP-1202964-A1 | CONDENSED INDOLINE DERIVATIVES AND THEIR USE AS 5HT, IN PARTICULAR 5HT2C, RECEPTOR LIGANDS | VERNALIS RESEARCH LIMITED (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012602-A1 | CONDENSED INDOLINE DERIVATIVES AND THEIR USE AS 5HT, IN PARTICULAR 5HT2C, RECEPTOR LIGANDS | VERNALIS RESEARCH LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |
| US-5633276-A | MELATONIN SYSTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-05-27 | — | — | US | disclosed |
| EP-0736028-A1 | INDOLINE DERIVATIVES, METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | GLAXO GROUP LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017405-A1 | INDOLINE DERIVATIVES, METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | GLAXO GROUP LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| EP-0079683-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4514211-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0079683-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-05-25 | — | — | EP | disclosed |
| US-3963717-A | ANTIINFLAMMATORY, ANALGESIC | SANDOZ, INC. (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138985-A1 | Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders | TPH2, TPH1, HTR1D | ITGB2 2481/4885ICAM1 2192/4885ITGAL 3476/4885 |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | CKS1B, CSNK1A1, CKS2 | ITGB2 4374/4885ICAM1 3973/4885ITGAL 4349/4885 |
| US-20250326767-A1 | NOVEL BENZOTHIAZOLE DERIVATIVES | DYRK1A, DYRK4, DYRK2 | ITGB2 4525/4885ICAM1 4214/4885ITGAL 4392/4885 |
| US-20250115618-A1 | SULFONIMIDAMIDE COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | IL1A, IL18, IL1B | ITGB2 4488/4885ICAM1 191/4885ITGAL 4527/4885 |
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | MAPT, MNAT1, MAT2A | ITGB2 3815/4885ICAM1 4867/4885ITGAL 4821/4885 |
| US-12234245-B2 | Sulfonimidamide compounds as inhibitors of interleukin-1 activity | IL1A, IL18, IL1B | ITGB2 4488/4885ICAM1 191/4885ITGAL 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.