Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974715 | 0.84 | MLYCD (0.50) | ALDH1A1SMN1; SMN2HPGDRAB9AKMT2A | |
| SCHEMBL10477068 | 0.82 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2HPGDRAB9AMAOB | |
| SCHEMBL11086112 | 0.80 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDRAB9AMAOB | |
| SCHEMBL28284714 | 0.79 | MEN1 (0.61) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL1004649 | 0.78 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL6284986 | 0.78 | KMT2A (0.64) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL1659309 | 0.78 | HPGD (0.73) | ALDH1A1SMN1; SMN2HPGDPARP10PARP4 | |
| SCHEMBL6634186 | 0.78 | MAPT (0.61) | SMN1; SMN2HPGDRAB9AKMT2AMEN1 | |
| SCHEMBL11308053 | 0.77 | KMT2A (0.50) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL6626857 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | claimed |
| CN-109689664-A | The quinoline and azepine quinoline compound that tricyclic heteroaryl as PAR4 inhibitor replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-109689664-A | The quinoline and azepine quinoline compound that tricyclic heteroaryl as PAR4 inhibitor replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |