Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072938 | 0.86 | SUCNR1 (0.46) | MAPK8MAPK10HTTGLAPOLB | |
| SCHEMBL29618172 | 0.86 | TSHR (0.52) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL8766226 | 0.86 | TSHR (0.52) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL649658 | 0.86 | TSHR (0.52) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL28125465 | 0.84 | GAA (0.47) | HPGDHTTGLAPOLBGAA | |
| SCHEMBL436804 | 0.82 | GAA (0.59) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL29404322 | 0.82 | GAA (0.59) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL17783721 | 0.82 | LTA4H (0.41) | MAPK8MAPK10HPGDHTTPOLB | |
| SCHEMBL31402349 | 0.81 | TSHR (0.52) | GLAPOLBGAATSHRBACE1 | |
| SCHEMBL29510560 | 0.81 | TSHR (0.47) | GLAPOLBGAATSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651208-B | N-aryl sulfonamide compound, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-01-04 | — | — | CN | disclosed |
| CN-109651208-A | N- arylsulfonamides compound, medical composition and its use | 中国科学院上海药物研究所 | 2019-04-19 | — | — | CN | disclosed |