SCHEMBL28286751

SCHEMBL28286751

NCCCC(N)(N)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 14/20 0.65
KCNH2 Q12809 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KCNN4 O15554 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3630705 0.84 KIF11 (0.68) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL3985816 0.82 KIF11 (0.65) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL847003 0.80 KIF11 (0.44) KIF11KCNN4TAAR1
SCHEMBL1660722 0.79 KCNN4 (0.46) KIF11KCNN4TAAR1
SCHEMBL2679441 0.79 KIF11 (1.00) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL8217294 0.78 MAOA (0.48) TAAR1MAOA
SCHEMBL28193226 0.78 SCN5A (0.42) KIF11KCNN4TAAR1
Bromide SCHEMBL14976365 0.77 KIF11 (0.95) KIF11KCNH2CYP3A4CYP2D6CYP2C9
Water SCHEMBL11129297 0.77 KIF11 (0.95) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL28472455 0.77 KIF11 (0.59) KIF11KCNH2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107216260-B A kind of compound and its application as epoxy hardener 雅安市弘利展化工有限公司 2019-04-12 CN disclosed