Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196440 | 0.89 | ALDH1A1 (0.61) | TSHRALDH1A1ANPEPHTTHDAC1 | |
| SCHEMBL13196424 | 0.87 | ALDH1A1 (0.44) | LMNAALDH1A1ANPEPHDAC1HDAC2 | |
| SCHEMBL2782119 | 0.84 | ANPEP (0.37) | TSHRANPEPHDAC1HDAC2 | |
| SCHEMBL2779726 | 0.80 | LMNA (0.48) | LMNATSHRALDH1A1ANPEPHTT | |
| SCHEMBL13196425 | 0.78 | AR (0.34) | LMNAALDH1A1ANPEP | |
| SCHEMBL13196421 | 0.76 | ANPEP (0.47) | LMNATSHRALDH1A1ANPEPHDAC1 | |
| SCHEMBL13196392 | 0.75 | GAA (0.50) | ALDH1A1 | |
| SCHEMBL13196389 | 0.72 | CNR2 (0.56) | LMNATSHRALDH1A1ANPEPHDAC1 | |
| SCHEMBL3467419 | 0.70 | ANPEP (0.53) | TSHRANPEPHDAC1HDAC2HDAC3 | |
| SCHEMBL2781625 | 0.69 | ALDH1A1 (0.41) | LMNATSHRALDH1A1ANPEPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |