Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050216 | 0.83 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1KDM4EPOLBHPGD | |
| Hydrochloric Acid SCHEMBL9284310 | 0.82 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1KDM4EPOLBHPGD | |
| Tert-Butyl Formate SCHEMBL27524789 | 0.81 | SIGMAR1 (0.66) | SIGMAR1ALDH1A1POLBCXCR4CHRM2 | |
| Tert-Butyl Formate SCHEMBL27993846 | 0.80 | CXCR4 (0.48) | SIGMAR1ALDH1A1KDM4EPOLBCXCR4 | |
| Tert-Butyl Formate SCHEMBL27844700 | 0.79 | HPGD (0.51) | SIGMAR1ALDH1A1KDM4EHPGDCXCR4 | |
| Tert-Butyl Formate SCHEMBL27981789 | 0.79 | CXCR4 (0.47) | SIGMAR1ALDH1A1KDM4EPOLBHPGD | |
| Tert-Butyl Formate SCHEMBL28777983 | 0.79 | LMNA (0.48) | SIGMAR1ALDH1A1CXCR4CHRM2CHRM1 | |
| Tert-Butyl Formate SCHEMBL28831465 | 0.78 | SIGMAR1 (0.45) | SIGMAR1CXCR4CHRM2CHRM1MEN1 | |
| Tert-Butyl Formate SCHEMBL28289206 | 0.78 | SIGMAR1 (0.42) | SIGMAR1HPGDCXCR4CHRM2CHRM1 | |
| Tert-Butyl Formate SCHEMBL28872096 | 0.77 | KMT2A (0.43) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |